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br Acknowledgments br Introduction Polyphenols are aromatic
2020-07-30

Acknowledgments Introduction Polyphenols are aromatic molecules that contain multiple phenolic hydroxyl groups and are components of plant pigments with a bitter flavor. Polyphenols have been reported to be useful in anti-oxidative (Boots et al., 2008, Nakai et al., 2003) and anti-obesity (Ika
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The central role of TNF in inflammation and
2020-07-30

The central role of TNF-α in inflammation and the immune system is established (reviewed in Ref. [34]) where it regulates such cellular processes as cytokine induction, proliferation, differentiation, and apoptosis. In contrast to these roles, however, several studies have suggested a function for T
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The changes in chemokine expression described above parallel
2020-07-30

The changes in chemokine expression described above paralleled a significant inhibition in the expression pro-inflammatory cytokines including IL-1β1 and IL-1β 2, IFNγ and IFNγrel, TNF-α2, IL-12p35 and CSF-1. All of these have been previously implicated in the regulation of goldfish macrophage pro-i
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In terms of the viability neither
2020-07-30

In terms of the viability neither the BA3 nor the BA4 product has been compromised, probably due to the physiology of the microorganism. To successfully formulate CPA-8, the endospore form was used (Gotor-Vila et al., 2017d). The inherent stability of these structures enabled them to remain quiescen
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Another stream of chiller system models
2020-07-30

Another stream of chiller system models focused on FDD. Yan et al. (2018) used a back-tracing sequential forward feature selection algorithm to select the most significant features for FDD and then used the support vector machine for measuring accuracy. Li and Hu (2018) considered the density-based
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The majority of pro inflammatory cytokines are regulated by
2020-07-30

The majority of pro-inflammatory cytokines are regulated by NFκB, and recently, it has been found that p38 MAPK partly regulates NFκB-driven gene FITC, Fluorescein isothiocyanate by increasing the association of the basal transcriptional factor, TATA-binding protein, with the C terminus of p65 subun
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This study focuses on mechanisms of reciprocity between
2020-07-29

This study focuses on mechanisms of reciprocity between DGTS and PC in fungi during Pi starvation. We report changes in expression of the BTA1 gene and two PC biosynthesis genes during phosphate starvation of F. velutipes culture. We describe the deduced amino fty720 sequence and genomic structure o
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PTEN resides at the q
2020-07-28

PTEN resides at the 10q23 locus and encodes a 403 amino Amsacrine mg (aa) protein with an N-terminal phosphatase domain (Li et al., 1997, Steck et al., 1997). The primary substrate of PTEN phosphatase is phosphatidylinositol-3,4,5-triphosphate (PIP3), a critical messenger for activation of the phos
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Although the pathophysiology of RLS is not fully
2020-07-28

Although the pathophysiology of RLS is not fully understood, evidence indicates that both iron deficiency and dopaminergic abnormalities are involved in its etiology. As iron is a major cofactor in dopaminergic neurotransmission, iron deficits may produce dopaminergic changes that exacerbate RLS sym
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br Material and Methods br Results br
2020-07-28

Material and Methods Results Discussion Metabolism of DAG by DGKζ phosphorylation is an important mechanism downstream of the TCR that limits T cell responses in naïve T cells. DGKζ deficiency also confers enhanced antitumor potential on pre-activated CD8+ T clemastine synthesis (Riese et a
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br Author contributions br Disclosure statement br Transpare
2020-07-28

Author contributions Disclosure statement Transparency document Acknowledgements This work is part of a research program, which is financed by the Province of Fryslân (01120657), the Netherlands and Alfasigma Nederland B.V (direct contribution to grant number 01120657). Introduction
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Knockdown of CPG led to an increase
2020-07-28

Knockdown of CPG2 led to an increase in postsynaptic clathrin-coated vesicles, some trafficking NMDA receptors, and a disruption of glutamate receptor internalization. This phenotype is similar to that seen in presynaptic terminals of organisms with mutations of endophilin or synaptojanin, where the
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Collagen genes encode long polypeptidic chains called
2020-07-28

Collagen genes encode long polypeptidic chains called α-chains that contain unique structural signature, the presence in their primary structure of the [Gly-X-Y] amino-acid repeats, where X and Y are often a proline and a hydroxyproline respectively. This results in the formation of a triple helix,
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In conclusion we demonstrated a significantly
2020-07-28

In conclusion, we demonstrated a significantly increased duration of CMV reactivation and a significantly increased incidence of CMV disease in CMV seropositive patients transplanted with a CMV seronegative donor (R+D−) compared to CMV seropositive patients transplanted with a CMV seropositive donor
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Taking all the data together we propose
2020-07-27

Taking all the data together, we propose the possible mechanism of glyphosate-induce cell proliferation via estrogen receptor signaling (Fig. 10). Glyphosate may bind to ERα followed by an activation step that starts with the phosphorylation of ERα and activation of other signaling proteins by phosp
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